Motif ID: MZF1.p2

Z-value: 3.295


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1



Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_159306532 9.362 NM_001163678
NM_003030
NM_006884
SHOX2


short stature homeobox 2


chr7_+_5289079 6.251 NM_001040661
NM_153247
SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr3_-_159306214 5.566


chr22_-_28972683 4.989 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr3_+_148610516 4.817 ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr1_+_2975590 4.689 NM_022114
NM_199454
PRDM16

PR domain containing 16

chr2_+_45022540 4.652 NM_005413
SIX3
SIX homeobox 3
chr11_+_17714070 4.447 NM_001112741
NM_004976
KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chr8_+_22513043 4.405 NM_001013842
NM_001198827
NM_173686
C8orf58


chromosome 8 open reading frame 58


chr4_-_1156959 4.120 NM_001128325
SPON2
spondin 2, extracellular matrix protein
chr13_+_113574925 4.074 NM_001143945
GAS6
growth arrest-specific 6
chr4_-_1156533 3.961 NM_012445
SPON2
spondin 2, extracellular matrix protein
chr2_-_200030944 3.891 NM_001172509
SATB2
SATB homeobox 2
chr2_+_104837004 3.806


chr4_-_46086528 3.775 NM_000807
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr14_-_60185659 3.729 NM_005982
SIX1
SIX homeobox 1
chr21_+_42946719 3.681 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr4_-_1156378 3.611 SPON2
spondin 2, extracellular matrix protein
chr3_-_148607096 3.537 NM_032153
ZIC4
Zic family member 4
chr6_-_32227645 3.522 PRRT1
proline-rich transmembrane protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 179 entries
Enrichment   P-value GO Accession GO Term
40.54 1.34e-03 GO:0033504 floor plate development
16.00 1.44e-02 GO:0048665 neuron fate specification
15.20 2.54e-03 GO:0060078 regulation of postsynaptic membrane potential
15.20 1.89e-02 GO:0060425 lung morphogenesis
13.82 3.13e-02 GO:0032330 regulation of chondrocyte differentiation
13.22 3.94e-02 GO:0021885 forebrain cell migration
12.52 1.44e-03 GO:0014032 neural crest cell development
11.20 3.19e-03 GO:0014033 neural crest cell differentiation
11.06 6.67e-04 GO:0048663 neuron fate commitment
10.92 3.83e-03 GO:0021987 cerebral cortex development
10.64 4.58e-03 GO:0021761 limbic system development
10.64 4.58e-03 GO:0051899 membrane depolarization
10.35 1.13e-03 GO:0021510 spinal cord development
9.86 3.67e-02 GO:0001708 cell fate specification
9.86 3.67e-02 GO:0021782 glial cell development
9.78 3.88e-04 GO:0021543 pallium development
9.44 5.31e-04 GO:0048704 embryonic skeletal system morphogenesis
9.08 1.75e-04 GO:0009953 dorsal/ventral pattern formation
8.69 2.68e-04 GO:0048762 mesenchymal cell differentiation
8.52 2.13e-02 GO:0001764 neuron migration

Gene overrepresentation in compartment category:

Showing 1 to 17 of 17 entries
Enrichment   P-value GO Accession GO Term
6.40 6.54e-03 GO:0033267 axon part
4.83 1.08e-04 GO:0030425 dendrite
4.79 8.99e-03 GO:0031225 anchored to membrane
4.51 1.51e-02 GO:0034703 cation channel complex
4.27 1.08e-04 GO:0005667 transcription factor complex
4.10 1.76e-03 GO:0034702 ion channel complex
4.09 2.60e-07 GO:0045202 synapse
3.96 1.04e-06 GO:0043005 neuron projection
3.91 2.39e-02 GO:0043025 neuronal cell body
3.82 2.60e-04 GO:0044456 synapse part
3.80 3.08e-02 GO:0044297 cell body
2.23 7.23e-03 GO:0042995 cell projection
2.01 4.83e-03 GO:0031226 intrinsic to plasma membrane
2.00 7.24e-03 GO:0005887 integral to plasma membrane
1.88 1.00e-04 GO:0044459 plasma membrane part
1.44 1.91e-02 GO:0005886 plasma membrane
1.42 3.28e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 20 of 36 entries
Enrichment   P-value GO Accession GO Term
14.31 4.14e-02 GO:0004970 ionotropic glutamate receptor activity
11.06 5.50e-06 GO:0008301 DNA bending activity
10.86 1.91e-09 GO:0003705 sequence-specific enhancer binding RNA polymerase II transcription factor activity
10.86 2.41e-02 GO:0008066 glutamate receptor activity
10.46 6.82e-10 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
8.11 7.98e-06 GO:0003704 specific RNA polymerase II transcription factor activity
6.27 1.29e-03 GO:0016566 specific transcriptional repressor activity
6.02 4.36e-08 GO:0000975 regulatory region DNA binding
6.02 4.36e-08 GO:0001067 regulatory region nucleic acid binding
6.02 4.36e-08 GO:0044212 transcription regulatory region DNA binding
5.96 1.53e-07 GO:0010843 promoter binding
5.57 1.89e-04 GO:0022843 voltage-gated cation channel activity
5.35 2.36e-23 GO:0043565 sequence-specific DNA binding
4.96 4.23e-03 GO:0003690 double-stranded DNA binding
4.71 1.05e-07 GO:0016563 transcription activator activity
4.67 2.99e-07 GO:0016564 transcription repressor activity
4.56 7.94e-04 GO:0005244 voltage-gated ion channel activity
4.56 7.94e-04 GO:0022832 voltage-gated channel activity
4.49 2.49e-24 GO:0001071 nucleic acid binding transcription factor activity
4.49 2.49e-24 GO:0003700 sequence-specific DNA binding transcription factor activity