Motif ID: MTF1.p2

Z-value: 3.273


Transcription factors associated with MTF1.p2:

Gene SymbolEntrez IDGene Name
MTF1 4520 metal-regulatory transcription factor 1



Activity profile for motif MTF1.p2.

activity profile for motif MTF1.p2


Sorted Z-values histogram for motif MTF1.p2

Sorted Z-values for motif MTF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MTF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_121893468 6.163 NM_021021
 SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr15_-_27650218 5.519 NM_015307
 FAM189A1
family with sequence similarity 189, member A1
chr14_+_101097440 5.092 NM_001362
 DIO3
deiodinase, iodothyronine, type III
chr8_-_121893449 4.817 SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr5_-_11957127 4.781 CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr9_+_90339835 4.669 NM_001161625
NM_145283
 NXNL2

nucleoredoxin-like 2

chr8_+_56177567 4.544 NM_052898
 XKR4
XK, Kell blood group complex subunit-related family, member 4
chr18_+_74841262 4.410 NM_171999
 SALL3
sal-like 3 (Drosophila)
chr10_-_103525646 4.167 NM_006119
NM_033163
NM_033164
NM_033165
 FGF8



fibroblast growth factor 8 (androgen-induced)



chr5_-_11956964 4.036 NM_001332
 CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr19_+_1704661 4.031 NM_001080488
 ONECUT3
one cut homeobox 3
chr8_-_121892877 3.791 SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr8_-_121893196 3.789


chr8_-_140784416 3.752 NM_016601
 KCNK9
potassium channel, subfamily K, member 9
chr11_-_2863536 3.607 NM_000076
NM_001122630
NM_001122631
 CDKN1C


cyclin-dependent kinase inhibitor 1C (p57, Kip2)


chr9_+_139892049 3.567 NM_000718
 CACNA1B
calcium channel, voltage-dependent, N type, alpha 1B subunit
chr10_+_83625049 3.529 NM_001010848
NM_001165972
 NRG3

neuregulin 3

chr16_-_87535106 3.501 NM_175931
 CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr2_+_74595073 3.461 NM_016170
 TLX2
T-cell leukemia homeobox 2
chr16_-_51138306 3.398 NM_001080430
 TOX3
TOX high mobility group box family member 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 81 entries
Enrichment   P-value GO Accession GO Term
9.75 3.55e-02 GO:0001656 metanephros development
6.50 3.61e-02 GO:0042063 gliogenesis
5.85 2.73e-02 GO:0051924 regulation of calcium ion transport
5.74 3.19e-02 GO:0001822 kidney development
5.52 4.34e-02 GO:0072001 renal system development
5.50 2.35e-03 GO:0045165 cell fate commitment
5.12 1.95e-03 GO:0030900 forebrain development
5.11 1.26e-02 GO:0001655 urogenital system development
4.87 8.59e-08 GO:0007420 brain development
4.79 4.15e-11 GO:0007417 central nervous system development
4.52 6.67e-04 GO:0050767 regulation of neurogenesis
4.27 6.69e-04 GO:0051960 regulation of nervous system development
3.96 4.80e-14 GO:0022008 neurogenesis
3.95 5.48e-13 GO:0048699 generation of neurons
3.94 5.52e-10 GO:0030182 neuron differentiation
3.93 1.76e-06 GO:0019226 transmission of nerve impulse
3.93 1.76e-06 GO:0035637 multicellular organismal signaling
3.92 1.55e-05 GO:0007268 synaptic transmission
3.81 1.60e-03 GO:0007411 axon guidance
3.77 1.42e-02 GO:0035295 tube development

Gene overrepresentation in compartment category:

Showing 1 to 17 of 17 entries
Enrichment   P-value GO Accession GO Term
11.21 1.38e-02 GO:0034704 calcium channel complex
9.75 5.87e-03 GO:0043679 axon terminus
9.29 7.82e-03 GO:0044306 neuron projection terminus
6.84 4.10e-03 GO:0033267 axon part
5.76 4.03e-02 GO:0014069 postsynaptic density
4.78 7.06e-04 GO:0030424 axon
4.53 4.05e-06 GO:0044456 synapse part
4.13 7.17e-03 GO:0030425 dendrite
4.07 1.28e-06 GO:0043005 neuron projection
3.87 6.81e-06 GO:0045202 synapse
3.06 8.99e-03 GO:0031012 extracellular matrix
2.63 4.90e-03 GO:0030054 cell junction
2.38 2.02e-03 GO:0042995 cell projection
2.01 7.84e-06 GO:0044459 plasma membrane part
1.57 3.00e-04 GO:0005886 plasma membrane
1.55 5.73e-04 GO:0071944 cell periphery
1.35 6.17e-03 GO:0044425 membrane part

Gene overrepresentation in function category:

Showing 1 to 20 of 23 entries
Enrichment   P-value GO Accession GO Term
15.29 2.73e-02 GO:0004970 ionotropic glutamate receptor activity
14.44 3.47e-02 GO:0005234 extracellular-glutamate-gated ion channel activity
12.50 1.03e-02 GO:0005245 voltage-gated calcium channel activity
11.61 1.50e-02 GO:0008066 glutamate receptor activity
5.91 4.47e-02 GO:0005262 calcium channel activity
5.20 5.85e-03 GO:0015276 ligand-gated ion channel activity
5.20 5.85e-03 GO:0022834 ligand-gated channel activity
4.58 1.74e-02 GO:0022843 voltage-gated cation channel activity
4.50 8.97e-03 GO:0008083 growth factor activity
4.17 8.40e-03 GO:0005244 voltage-gated ion channel activity
4.17 8.40e-03 GO:0022832 voltage-gated channel activity
4.11 5.66e-05 GO:0022836 gated channel activity
3.70 3.83e-03 GO:0005261 cation channel activity
3.53 1.60e-04 GO:0022838 substrate-specific channel activity
3.51 2.56e-08 GO:0043565 sequence-specific DNA binding
3.42 2.62e-04 GO:0015267 channel activity
3.42 2.72e-04 GO:0022803 passive transmembrane transporter activity
3.41 4.95e-04 GO:0005216 ion channel activity
2.80 5.53e-07 GO:0030528 transcription regulator activity
2.71 3.36e-06 GO:0001071 nucleic acid binding transcription factor activity