Motif ID: IRF1,2,7.p3

Z-value: 2.504


Transcription factors associated with IRF1,2,7.p3:

Gene SymbolEntrez IDGene Name
IRF1 3659 interferon regulatory factor 1
IRF2 3660 interferon regulatory factor 2
IRF7 3665 interferon regulatory factor 7



Activity profile for motif IRF1,2,7.p3.

activity profile for motif IRF1,2,7.p3


Sorted Z-values histogram for motif IRF1,2,7.p3

Sorted Z-values for motif IRF1,2,7.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of IRF1,2,7.p3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_34521945 4.696 SRP54
signal recognition particle 54kDa
chr12_+_111900650 4.014 NM_001032731
NM_002535
NM_016817
 OAS2


2'-5'-oligoadenylate synthetase 2, 69/71kDa


chr9_-_32516164 3.867 NM_014314
 DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr6_-_46997579 3.539 NM_001098518
 GPR116
G protein-coupled receptor 116
chr14_+_34521854 3.357 NM_001146282
NM_003136
 SRP54

signal recognition particle 54kDa

chr6_+_26473376 3.272 NM_001197247
NM_001197249
NM_007047
NM_001197248
 BTN3A2



butyrophilin, subfamily 3, member A2



chr13_-_42464301 3.170 NM_001002264
NM_033255
 EPSTI1

epithelial stromal interaction 1 (breast)

chr14_+_31100330 3.121 NM_025152
 NUBPL
nucleotide binding protein-like
chr20_+_1194959 3.117 NM_014723
 SNPH
syntaphilin
chr6_+_26510443 3.045 NM_001145008
NM_001145009
NM_007048
NM_194441
 BTN3A1



butyrophilin, subfamily 3, member A1



chr6_+_26548678 2.961 NM_006994
NM_197974
 BTN3A3

butyrophilin, subfamily 3, member A3

chr20_-_55628852 2.811 NM_001160417
NM_001160418
NM_001160419
NM_030776
 ZBP1



Z-DNA binding protein 1



chr2_-_1905508 2.707 MYT1L
myelin transcription factor 1-like
chr2_-_70329067 2.697 NM_022037
NM_022173
 TIA1

TIA1 cytotoxic granule-associated RNA binding protein

chr2_+_122229590 2.649 NM_004622
 TSN
translin
chr20_-_5048443 2.596 NM_182649
 PCNA
proliferating cell nuclear antigen
chr7_+_154351087 2.583 LOC100132707
hypothetical LOC100132707
chr16_+_55580910 2.574 NM_032206
 NLRC5
NLR family, CARD domain containing 5
chr12_+_27568311 2.533 NM_001198915
NM_001198916
NM_003622
NM_177444
 PPFIBP1



PTPRF interacting protein, binding protein 1 (liprin beta 1)



chr7_-_92615593 2.481 NM_152703
 SAMD9L
sterile alpha motif domain containing 9-like

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 13 of 13 entries
Enrichment   P-value GO Accession GO Term
19.25 2.89e-02 GO:0032480 negative regulation of type I interferon production
15.04 1.08e-02 GO:0032479 regulation of type I interferon production
13.97 2.37e-03 GO:0060337 type I interferon-mediated signaling pathway
13.97 2.37e-03 GO:0071357 cellular response to type I interferon
13.75 2.60e-03 GO:0034340 response to type I interferon
11.64 3.80e-02 GO:0060333 interferon-gamma-mediated signaling pathway
10.83 1.05e-02 GO:0034341 response to interferon-gamma
6.68 1.05e-06 GO:0045087 innate immune response
5.11 1.45e-02 GO:0034097 response to cytokine stimulus
5.06 4.01e-02 GO:0001817 regulation of cytokine production
3.78 5.91e-04 GO:0006955 immune response
3.31 7.06e-03 GO:0006952 defense response
2.96 1.15e-03 GO:0002376 immune system process

Nothing significant found in compartment category.

Nothing significant found in function category.