Motif ID: HMGA1,2.p2

Z-value: 3.308


Transcription factors associated with HMGA1,2.p2:

Gene SymbolEntrez IDGene Name
HMGA1 3159 high mobility group AT-hook 1
HMGA2 8091 high mobility group AT-hook 2



Activity profile for motif HMGA1,2.p2.

activity profile for motif HMGA1,2.p2


Sorted Z-values histogram for motif HMGA1,2.p2

Sorted Z-values for motif HMGA1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HMGA1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_150353179 4.500 NM_007113
TCHH
trichohyalin
chr12_-_94469357 3.771 NM_032147
USP44
ubiquitin specific peptidase 44
chr10_-_62002672 3.602 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr1_+_205344200 3.164 NM_000715
C4BPA
complement component 4 binding protein, alpha
chr3_-_152529999 3.156 NM_176894
P2RY13
purinergic receptor P2Y, G-protein coupled, 13
chr9_-_111253484 3.149 NM_001145369
NM_001145370
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr3_+_39346200 3.106 NM_005201
CCR8
chemokine (C-C motif) receptor 8
chr2_+_165860528 3.089 NM_001040143
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr13_+_107753764 3.078


chr3_-_114176401 3.041 NM_138806
NM_138939
NM_138940
NM_170780
CD200R1



CD200 receptor 1



chr12_-_9976173 2.968 NM_001130711
CLEC2A
C-type lectin domain family 2, member A
chr6_-_132987106 2.888 NM_001033080
TAAR2
trace amine associated receptor 2
chr11_-_18214891 2.782 NM_006512
SAA4
serum amyloid A4, constitutive
chr8_-_20084892 2.689 NM_001135691
NM_001142324
NM_001142325
NM_003053
SLC18A1



solute carrier family 18 (vesicular monoamine), member 1



chr11_+_113280727 2.638 NM_006028
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chr3_+_143824955 2.455 NM_002670
PLS1
plastin 1
chr15_-_41195994 2.421 RPS3A
ribosomal protein S3A
chr11_-_40271086 2.409 LRRC4C
leucine rich repeat containing 4C
chr12_-_10850845 2.382 NM_023918
TAS2R8
taste receptor, type 2, member 8
chr11_-_85146691 2.342 NM_001162951
NM_001162953
SYTL2

synaptotagmin-like 2


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 2 of 2 entries
Enrichment   P-value GO Accession GO Term
16.31 7.52e-03 GO:0060338 regulation of type I interferon-mediated signaling pathway
2.85 1.53e-02 GO:0006955 immune response

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
Enrichment   P-value GO Accession GO Term
2.81 7.58e-05 GO:0044421 extracellular region part
2.73 3.40e-03 GO:0005615 extracellular space
2.24 2.17e-05 GO:0005576 extracellular region
1.53 2.61e-02 GO:0005886 plasma membrane
1.50 3.93e-02 GO:0071944 cell periphery
1.48 4.20e-03 GO:0031224 intrinsic to membrane
1.47 7.56e-03 GO:0016021 integral to membrane
1.43 4.52e-03 GO:0044425 membrane part

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
36.70 1.08e-02 GO:0005132 interferon-alpha/beta receptor binding
4.43 3.93e-02 GO:0005125 cytokine activity
2.74 3.18e-03 GO:0004930 G-protein coupled receptor activity
2.39 1.88e-03 GO:0004888 transmembrane receptor activity
2.35 8.40e-05 GO:0004872 receptor activity
2.02 1.69e-03 GO:0004871 signal transducer activity
2.02 1.69e-03 GO:0060089 molecular transducer activity