Motif ID: HLF.p2

Z-value: 2.146


Transcription factors associated with HLF.p2:

Gene SymbolEntrez IDGene Name
HLF 3131 hepatic leukemia factor



Activity profile for motif HLF.p2.

activity profile for motif HLF.p2


Sorted Z-values histogram for motif HLF.p2

Sorted Z-values for motif HLF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HLF.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_113601608 4.609 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr11_+_111552298 4.393 NM_001037290
BCO2
beta-carotene oxygenase 2
chr2_-_113310796 4.315 NM_000576
IL1B
interleukin 1, beta
chr1_-_177106702 3.484 NM_004673
ANGPTL1
angiopoietin-like 1
chr2_+_64540843 3.462 HSPC159
galectin-related protein
chr4_-_77147625 3.232 NM_002416
CXCL9
chemokine (C-X-C motif) ligand 9
chr2_+_113601616 3.230 IL1RN
interleukin 1 receptor antagonist
chr11_-_102081654 2.910 NM_022122
MMP27
matrix metallopeptidase 27
chr6_-_30151526 2.487 NM_170769
NM_025236
RNF39

ring finger protein 39

chr9_+_116131889 2.442 NM_000608
ORM2
orosomucoid 2
chr1_-_205210567 2.357 NM_001122979
NM_001170631
NM_032029
FCAMR


Fc receptor, IgA, IgM, high affinity


chr12_-_51132129 2.346 NM_005555
KRT6B
keratin 6B
chr10_-_14412813 2.273 NM_018027
FRMD4A
FERM domain containing 4A
chr9_+_116125123 2.248 NM_000607
ORM1
orosomucoid 1
chr7_+_128136347 2.226 FAM71F1
family with sequence similarity 71, member F1
chr3_-_152585226 2.152 NM_022788
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr11_-_10487212 2.039 NM_001190702
MTRNR2L8
MT-RNR2-like 8
chr6_-_169395972 2.024 NM_003247
THBS2
thrombospondin 2
chr5_-_39400319 1.970 NM_001737
C9
complement component 9
chr12_-_103846186 1.937 NM_032148
SLC41A2
solute carrier family 41, member 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 5 of 5 entries
Enrichment   P-value GO Accession GO Term
298.70 4.70e-03 GO:0070163 regulation of adiponectin secretion
37.35 2.89e-02 GO:0032755 positive regulation of interleukin-6 production
10.09 9.22e-05 GO:0006954 inflammatory response
4.84 1.95e-03 GO:0006952 defense response
4.78 8.39e-04 GO:0009611 response to wounding

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
Enrichment   P-value GO Accession GO Term
5.57 7.85e-06 GO:0005615 extracellular space
4.91 4.53e-06 GO:0044421 extracellular region part
4.04 4.16e-09 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
Enrichment   P-value GO Accession GO Term
99.58 1.39e-02 GO:0005152 interleukin-1 receptor antagonist activity
99.58 1.39e-02 GO:0030492 hemoglobin binding
35.86 6.54e-03 GO:0001608 nucleotide receptor activity, G-protein coupled
35.86 6.54e-03 GO:0045028 purinergic nucleotide receptor activity, G-protein coupled
28.02 1.39e-02 GO:0001614 purinergic nucleotide receptor activity
28.02 1.39e-02 GO:0016502 nucleotide receptor activity
24.91 1.98e-02 GO:0035586 purinergic receptor activity
11.32 2.15e-04 GO:0005126 cytokine receptor binding
9.02 4.27e-03 GO:0005125 cytokine activity
3.75 5.00e-03 GO:0005102 receptor binding