Motif ID: GTF2I.p2

Z-value: 2.355


Transcription factors associated with GTF2I.p2:

Gene SymbolEntrez IDGene Name
GTF2I 2969 general transcription factor II, i



Activity profile for motif GTF2I.p2.

activity profile for motif GTF2I.p2


Sorted Z-values histogram for motif GTF2I.p2

Sorted Z-values for motif GTF2I.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GTF2I.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_17714070 5.132 NM_001112741
NM_004976
KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chrX_+_144707022 4.001 NM_001144003
NM_001144004
NM_001144005
NM_032539
SLITRK2



SLIT and NTRK-like family, member 2



chr15_-_86600658 3.518 NM_001007156
NM_001012338
NM_002530
NTRK3


neurotrophic tyrosine kinase, receptor, type 3


chr2_+_45022540 3.366 NM_005413
SIX3
SIX homeobox 3
chr12_+_6800950 3.023 NM_014449
NM_019858
GPR162

G protein-coupled receptor 162

chr18_-_28606839 2.911 NM_020805
KLHL14
kelch-like 14 (Drosophila)
chr14_-_60185659 2.898 NM_005982
SIX1
SIX homeobox 1
chr13_+_99431417 2.868


chrX_+_136476353 2.865 ZIC3
Zic family member 3 (odd-paired homolog, Drosophila)
chr18_-_21184824 2.813


chr12_+_93066370 2.713 NM_005761
PLXNC1
plexin C1
chr13_+_57103944 2.668 PCDH17
protocadherin 17
chr17_-_44047299 2.666 NM_024016
HOXB8
homeobox B8
chr13_+_57103789 2.665 NM_001040429
PCDH17
protocadherin 17
chr1_+_26609893 2.599 LIN28A
lin-28 homolog A (C. elegans)
chr8_+_104582151 2.510 NM_001100117
RIMS2
regulating synaptic membrane exocytosis 2
chr14_-_36058648 2.501 NM_003317
NKX2-1
NK2 homeobox 1
chr14_-_23117614 2.496 JPH4
junctophilin 4
chr2_-_200030944 2.419 NM_001172509
SATB2
SATB homeobox 2
chr11_-_27697768 2.372 NM_001143807
BDNF
brain-derived neurotrophic factor

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 137 entries
Enrichment   P-value GO Accession GO Term
18.85 4.65e-02 GO:0031128 developmental induction
18.85 4.65e-02 GO:0045168 cell-cell signaling involved in cell fate commitment
16.71 1.22e-03 GO:0060021 palate development
13.93 2.38e-02 GO:0009880 embryonic pattern specification
12.68 6.37e-03 GO:0048704 embryonic skeletal system morphogenesis
12.26 4.47e-02 GO:0001764 neuron migration
11.14 2.50e-08 GO:0009952 anterior/posterior pattern formation
10.98 1.48e-02 GO:0009953 dorsal/ventral pattern formation
10.86 3.10e-03 GO:0048706 embryonic skeletal system development
10.49 1.76e-11 GO:0003002 regionalization
9.53 7.41e-03 GO:0021537 telencephalon development
9.52 1.67e-03 GO:0061138 morphogenesis of a branching epithelium
9.43 7.97e-03 GO:0051216 cartilage development
9.31 7.47e-14 GO:0007389 pattern specification process
9.19 4.08e-02 GO:0060485 mesenchyme development
9.03 1.06e-02 GO:0048754 branching morphogenesis of a tube
8.57 2.26e-04 GO:0060562 epithelial tube morphogenesis
8.41 1.69e-02 GO:0001822 kidney development
8.17 2.04e-02 GO:0048736 appendage development
8.17 2.04e-02 GO:0060173 limb development

Gene overrepresentation in compartment category:

Showing 1 to 14 of 14 entries
Enrichment   P-value GO Accession GO Term
20.42 5.45e-03 GO:0043195 terminal button
16.56 1.63e-03 GO:0042734 presynaptic membrane
15.32 2.41e-03 GO:0043679 axon terminus
14.59 3.08e-03 GO:0044306 neuron projection terminus
9.68 4.97e-03 GO:0033267 axon part
8.28 5.07e-05 GO:0045211 postsynaptic membrane
7.26 2.62e-08 GO:0044456 synapse part
7.14 5.85e-05 GO:0030425 dendrite
6.02 5.09e-08 GO:0045202 synapse
5.57 6.57e-04 GO:0005667 transcription factor complex
5.54 1.41e-02 GO:0030424 axon
5.31 7.25e-03 GO:0034702 ion channel complex
3.52 4.31e-02 GO:0043005 neuron projection
3.02 3.19e-02 GO:0030054 cell junction

Gene overrepresentation in function category:

Showing 1 to 20 of 31 entries
Enrichment   P-value GO Accession GO Term
18.85 1.09e-02 GO:0005245 voltage-gated calcium channel activity
17.50 1.47e-02 GO:0008066 glutamate receptor activity
11.92 3.86e-04 GO:0005230 extracellular ligand-gated ion channel activity
11.14 1.66e-02 GO:0008301 DNA bending activity
10.72 7.89e-04 GO:0042165 neurotransmitter binding
10.36 4.84e-03 GO:0030594 neurotransmitter receptor activity
10.21 1.10e-03 GO:0003705 sequence-specific enhancer binding RNA polymerase II transcription factor activity
9.53 1.73e-03 GO:0003704 specific RNA polymerase II transcription factor activity
9.23 2.16e-03 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
8.83 1.67e-04 GO:0015276 ligand-gated ion channel activity
8.83 1.67e-04 GO:0022834 ligand-gated channel activity
6.91 4.24e-03 GO:0022843 voltage-gated cation channel activity
6.11 4.85e-06 GO:0022836 gated channel activity
5.25 2.96e-02 GO:0005244 voltage-gated ion channel activity
5.25 2.96e-02 GO:0022832 voltage-gated channel activity
5.14 3.08e-04 GO:0016563 transcription activator activity
5.11 4.31e-10 GO:0043565 sequence-specific DNA binding
5.06 3.81e-02 GO:0010843 promoter binding
4.83 1.03e-04 GO:0005216 ion channel activity
4.75 1.26e-04 GO:0022838 substrate-specific channel activity