Motif ID: EN1,2.p2

Z-value: 2.262


Transcription factors associated with EN1,2.p2:

Gene SymbolEntrez IDGene Name
EN1 2019 engrailed homeobox 1
EN2 2020 engrailed homeobox 2



Activity profile for motif EN1,2.p2.

activity profile for motif EN1,2.p2


Sorted Z-values histogram for motif EN1,2.p2

Sorted Z-values for motif EN1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EN1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_30188845 4.050 NM_007028
 TRIM31
tripartite motif containing 31
chr12_+_10351683 3.276 NM_002262
NM_007334
 KLRD1

killer cell lectin-like receptor subfamily D, member 1

chr10_+_114144512 3.104 ACSL5
acyl-CoA synthetase long-chain family member 5
chr1_+_157526127 2.791 NM_002001
 FCER1A
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
chr11_-_123182266 2.550 NM_001005325
 OR6M1
olfactory receptor, family 6, subfamily M, member 1
chr1_+_31823097 2.359 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr2_+_96355661 2.330 NM_178495
NM_001163524
 ITPRIPL1

inositol 1,4,5-triphosphate receptor interacting protein-like 1

chr6_-_119512035 2.233 NM_001100411
 FAM184A
family with sequence similarity 184, member A
chr5_-_77880731 2.182 LHFPL2
lipoma HMGIC fusion partner-like 2
chr9_-_110658030 1.989 NM_006686
 ACTL7B
actin-like 7B
chr12_+_63510481 1.984


chr1_+_200775864 1.895 NM_001197131
 PPP1R12B
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr22_+_19660361 1.892 AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr3_+_120375053 1.883 NM_006952
 UPK1B
uroplakin 1B
chr12_-_103846186 1.869 NM_032148
 SLC41A2
solute carrier family 41, member 2
chr1_-_202726068 1.798 NM_002646
 PIK3C2B
phosphoinositide-3-kinase, class 2, beta polypeptide
chr11_-_58947001 1.781 NM_001001954
 OR5A2
olfactory receptor, family 5, subfamily A, member 2
chr12_+_54316910 1.728 NM_206899
 OR10P1
olfactory receptor, family 10, subfamily P, member 1
chr4_+_157044296 1.720 NM_005651
 TDO2
tryptophan 2,3-dioxygenase
chr3_-_38967055 1.696 NM_014139
 SCN11A
sodium channel, voltage-gated, type XI, alpha subunit

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
Enrichment   P-value GO Accession GO Term
2.89 3.23e-02 GO:0000267 cell fraction
1.89 4.32e-03 GO:0071944 cell periphery
1.86 8.74e-03 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
Enrichment   P-value GO Accession GO Term
230.08 1.88e-03 GO:0008389 coumarin 7-hydroxylase activity
4.95 1.91e-02 GO:0004984 olfactory receptor activity
2.91 1.29e-02 GO:0004888 transmembrane receptor activity
2.62 9.06e-03 GO:0004872 receptor activity
2.39 1.26e-02 GO:0004871 signal transducer activity
2.39 1.26e-02 GO:0060089 molecular transducer activity