Motif ID: CACAGUG

Z-value: 0.981


Mature miRNA associated with seed CACAGUG:

NamemiRBase Accession
hsa-miR-128 MIMAT0000424



Activity profile for motif CACAGUG.

activity profile for motif CACAGUG


Sorted Z-values histogram for motif CACAGUG

Sorted Z-values for motif CACAGUG



Network of associatons between targets according to the STRING database.



First level regulatory network of CACAGUG

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_108176901 2.691 NM_014421
DKK2
dickkopf homolog 2 (Xenopus laevis)
chr4_-_41849651 2.453 NM_001159547
NM_207406
BEND4

BEN domain containing 4

chr18_+_53253775 2.407 NM_004852
ONECUT2
one cut homeobox 2
chr3_-_129694717 2.293 NM_032638
GATA2
GATA binding protein 2
chr5_+_132176921 2.262 NM_175873
ANKRD43
ankyrin repeat domain 43
chr7_-_28964553 2.210 NM_014817
TRIL
TLR4 interactor with leucine-rich repeats
chr3_-_171786468 2.190 NM_020949
SLC7A14
solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
chr14_+_91859904 2.004 NM_153646
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr17_-_44047299 1.899 NM_024016
HOXB8
homeobox B8
chr15_+_30797466 1.851 NM_001191322
NM_001191323
NM_013372
GREM1


gremlin 1


chr7_+_154943466 1.769 NM_001427
EN2
engrailed homeobox 2
chr18_-_68685789 1.755 NM_138966
NETO1
neuropilin (NRP) and tolloid (TLL)-like 1
chr22_-_37569962 1.712 NM_014293
NPTXR
neuronal pentraxin receptor
chr12_-_80677223 1.672 NM_003625
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr21_-_38955487 1.648 NM_001136154
NM_004449
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr4_-_13155135 1.640 NM_001189
NKX3-2
NK3 homeobox 2
chr16_-_87535106 1.551 NM_175931
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr1_-_148155986 1.525 NM_014849
SV2A
synaptic vesicle glycoprotein 2A
chr2_+_5750229 1.506 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr7_-_103417198 1.496 NM_005045
NM_173054
RELN

reelin


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 29 entries
Enrichment   P-value GO Accession GO Term
315.30 3.55e-03 GO:0048791 calcium ion-dependent exocytosis of neurotransmitter
37.85 2.34e-02 GO:0007215 glutamate signaling pathway
14.09 9.56e-03 GO:0050804 regulation of synaptic transmission
13.83 1.57e-03 GO:0031644 regulation of neurological system process
12.73 1.56e-02 GO:0051969 regulation of transmission of nerve impulse
6.34 1.16e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
6.23 4.04e-03 GO:0048858 cell projection morphogenesis
6.23 1.31e-02 GO:0048812 neuron projection morphogenesis
6.17 4.33e-03 GO:0032990 cell part morphogenesis
6.09 1.49e-03 GO:0048666 neuron development
5.65 2.62e-02 GO:0031175 neuron projection development
5.59 2.83e-02 GO:0000904 cell morphogenesis involved in differentiation
5.27 1.51e-02 GO:0000902 cell morphogenesis
5.04 7.88e-03 GO:0030182 neuron differentiation
5.01 3.86e-04 GO:0022008 neurogenesis
5.00 2.29e-02 GO:0032989 cellular component morphogenesis
4.96 4.37e-04 GO:0048468 cell development
4.93 2.55e-02 GO:0030030 cell projection organization
4.91 1.35e-03 GO:0048699 generation of neurons
4.06 1.14e-04 GO:0007399 nervous system development

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
15.98 1.00e-02 GO:0014069 postsynaptic density
10.67 9.04e-03 GO:0045211 postsynaptic membrane
10.03 2.46e-03 GO:0030425 dendrite
8.81 2.63e-04 GO:0044456 synapse part
7.41 2.47e-04 GO:0043005 neuron projection
7.35 2.63e-04 GO:0045202 synapse
4.45 3.36e-02 GO:0030054 cell junction

Gene overrepresentation in function category:

Showing 1 to 15 of 15 entries
Enrichment   P-value GO Accession GO Term
57.34 3.65e-02 GO:0017075 syntaxin-1 binding
55.66 1.34e-03 GO:0004970 ionotropic glutamate receptor activity
52.56 1.61e-03 GO:0005234 extracellular-glutamate-gated ion channel activity
45.06 1.17e-04 GO:0008066 glutamate receptor activity
36.40 5.03e-03 GO:0019905 syntaxin binding
30.53 8.60e-03 GO:0000149 SNARE binding
20.14 2.99e-02 GO:0005231 excitatory extracellular ligand-gated ion channel activity
8.45 2.05e-02 GO:0005244 voltage-gated ion channel activity
8.45 2.05e-02 GO:0022832 voltage-gated channel activity
7.35 2.83e-03 GO:0022836 gated channel activity
5.81 1.23e-02 GO:0005216 ion channel activity
5.72 1.36e-02 GO:0022838 substrate-specific channel activity
5.55 1.64e-02 GO:0015267 channel activity
5.54 1.66e-02 GO:0022803 passive transmembrane transporter activity
3.06 4.79e-02 GO:0005215 transporter activity