Motif ID: ADNP_IRX_SIX_ZHX.p2

Z-value: 1.348


Transcription factors associated with ADNP_IRX_SIX_ZHX.p2:

Gene SymbolEntrez IDGene Name
ADNP 23394 activity-dependent neuroprotector homeobox
IRX4 50805 iroquois homeobox 4
IRX5 10265 iroquois homeobox 5
SIX2 10736 SIX homeobox 2
SIX5 147912 SIX homeobox 5
ZHX1 11244 zinc fingers and homeoboxes 1
ZHX2 22882 zinc fingers and homeoboxes 2
ZHX3 23051 zinc fingers and homeoboxes 3



Activity profile for motif ADNP_IRX_SIX_ZHX.p2.

activity profile for motif ADNP_IRX_SIX_ZHX.p2


Sorted Z-values histogram for motif ADNP_IRX_SIX_ZHX.p2

Sorted Z-values for motif ADNP_IRX_SIX_ZHX.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ADNP_IRX_SIX_ZHX.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_556968 1.988


chr6_+_12398514 1.872 NM_001168319
NM_001955
EDN1

endothelin 1

chr6_+_21701942 1.805 NM_003107
SOX4
SRY (sex determining region Y)-box 4
chr6_+_167445284 1.519 NM_004367
CCR6
chemokine (C-C motif) receptor 6
chr2_-_87102453 1.391 NM_002665
NM_001032392
PLGLB2
PLGLB1
plasminogen-like B2
plasminogen-like B1
chr11_+_113280727 1.366 NM_006028
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chr6_+_29249289 1.345 NM_030905
OR2J2
olfactory receptor, family 2, subfamily J, member 2
chr15_+_47502666 1.175 NM_002009
FGF7
fibroblast growth factor 7
chr4_+_74520796 1.173 NM_001134
AFP
alpha-fetoprotein
chr6_+_155579788 1.107 NM_001010927
TIAM2
T-cell lymphoma invasion and metastasis 2
chr7_+_129771865 1.060 NM_001127441
NM_001127442
NM_080385
CPA5


carboxypeptidase A5


chr6_-_89984214 1.032 NM_002042
GABRR1
gamma-aminobutyric acid (GABA) receptor, rho 1
chr1_+_557269 1.000


chr4_+_120029426 0.999 NM_001128933
NM_001128934
NM_133477
SYNPO2


synaptopodin 2


chr12_+_54172413 0.926 NM_001005519
OR6C68
olfactory receptor, family 6, subfamily C, member 68
chr6_+_29534109 0.903 NM_030883
OR2H1
olfactory receptor, family 2, subfamily H, member 1
chr3_-_33675484 0.901 CLASP2
cytoplasmic linker associated protein 2
chr2_-_69033515 0.882 NM_182536
GKN2
gastrokine 2
chr2_-_131073329 0.874 NM_032545
NM_001079530
CFC1
CFC1B
cripto, FRL-1, cryptic family 1
cripto, FRL-1, cryptic family 1B
chr1_+_198263352 0.862 NM_003822
NM_205860
NR5A2

nuclear receptor subfamily 5, group A, member 2


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 2 of 2 entries
Enrichment   P-value GO Accession GO Term
83.54 2.62e-02 GO:0035272 exocrine system development
6.22 1.01e-03 GO:0007166 cell surface receptor linked signaling pathway

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
Enrichment   P-value GO Accession GO Term
39.49 1.89e-02 GO:0005230 extracellular ligand-gated ion channel activity